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MDL 3140 · N.D. Florida · settlement in principle (2026)

Diagnosed with a meningioma (brain tumor) after Depo-Provera birth-control shots?

Research links repeated use of Depo-Provera (the medroxyprogesterone birth-control injection) to meningioma brain tumors. Cases against Pfizer are consolidated as MDL 3140, and a settlement in principle was reached in 2026. We never sell your information.

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◆ the case ◆
5,800+ Depo-Provera cases consolidated in the federal MDL (3140)
2024 year a major study linked prolonged use to meningioma risk
Dec 2025 FDA adds a meningioma warning to the Depo-Provera label
2026 Pfizer reaches a settlement in principle in the federal MDL

Why this is real and why it matters now

A large 2024 study associated long-term use of the injectable contraceptive medroxyprogesterone (Depo-Provera) with a markedly higher risk of intracranial meningioma. In December 2025 the FDA added a meningioma warning to the label. The federal cases are consolidated as MDL 3140 before Judge Casey Rodgers in the Northern District of Florida, and in June 2026 Pfizer and plaintiffs' leadership reached a settlement in principle.

The signal is recent and strong. A 2024 study of contraceptive use found that prolonged use of medroxyprogesterone acetate, the active ingredient in Depo-Provera, was associated with a substantially higher risk of developing an intracranial meningioma, a tumor of the membranes around the brain.

In December 2025 the FDA added a meningioma warning to the Depo-Provera label. The federal cases are consolidated as MDL 3140 before Judge Casey Rodgers in the Northern District of Florida. A June 2026 settlement in principle covers eligible plaintiffs already in the federal MDL; it does not resolve every case, and state-court options may remain.

What you might receive. Depo-Provera settlement terms have not yet been publicly disclosed; values will depend on diagnosis, treatment (including surgery), and duration of use.

The evidence

The documented basis for these claims:

How this case got here

  1. 1990s onward Depo-Provera is widely prescribed as a long-acting injectable contraceptive.
  2. 2024 A BMJ study links prolonged medroxyprogesterone use to higher meningioma risk.
  3. Early 2025 Lawsuits are filed and consolidated into MDL 3140 before Judge Casey Rodgers (N.D. Fla).
  4. Dec 2025 The FDA adds a meningioma warning to the Depo-Provera label.
  5. Jun 2026 Pfizer and plaintiffs' leadership reach a settlement in principle in the federal MDL.

Conditions covered by the Depo-Provera litigation

Meningioma is the core diagnosis; other brain-tumor diagnoses may be evaluated individually.

Intracranial meningioma

Primary

A tumor arising from the membranes surrounding the brain and spinal cord. Often requires surgery or radiation and long-term monitoring.

Other brain tumors

Secondary

Non-meningioma brain-tumor diagnoses are reviewed case by case; whether they fit the intake depends on the specific firm and facts.

Who qualifies

You likely qualify if

  • You received Depo-Provera injections, typically over a year or more
  • You were later diagnosed with an intracranial meningioma
  • Your injections and diagnosis appear in medical or pharmacy records

Worth checking if

  • You used Depo-Provera long-term but your diagnosis is recent or another brain-tumor type
  • A close relative used it, was diagnosed, and has since passed (wrongful-death claims may apply)

You probably don't qualify if

  • You never received Depo-Provera or medroxyprogesterone injections
  • You have no brain-tumor diagnosis and no symptoms

Used Depo-Provera and later diagnosed with a meningioma?

The 60-second check above tells you if your situation fits the criteria. Free, confidential, no obligation.

Check my eligibility →

How filing a Depo-Provera claim works

Four steps. After the first one, the attorney's team does almost everything.

  1. 1

    Take the 60-second eligibility check

    Three questions confirm the basics: Depo-Provera use, diagnosis, and attorney status.

    About 60 seconds.
  2. 2

    Free case review by a Depo-Provera attorney

    An attorney from the network reviews your answers and follows up to confirm your situation fits intake criteria.

    1 to 2 business days.
  3. 3

    Records gathered under HIPAA authorization

    If accepted, the intake team collects your imaging, pathology, treatment, and injection history.

    3 to 6 weeks.
  4. 4

    Claim filed in the litigation

    Once records are complete, your claim is filed. Your attorney handles it through resolution. You can withdraw before signing a representation agreement.

    Filing within 30 days of records being complete.

Why timing matters for Depo-Provera claims

Every state sets a filing deadline. With a settlement in principle now in place for the federal MDL, claim windows can move quickly.

If you are unsure whether you are still within the window, run the check now. The attorney review is free and the deadline question is evaluated first.

About the attorneys you'd be connected with

claimscout is not a law firm. We connect you with attorneys from a vetted network of firms that handle Depo-Provera (MDL 3140) claims.

claimscout is a referral service. We do not provide legal advice and are not a substitute for an attorney-client relationship. Sponsored attorney advertising. Past results do not guarantee future outcomes.

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note from the founder.

You do not need to prove the medicine on Depo-Provera. A major study and an FDA label change already did. Your job is to confirm you received the shots and were diagnosed with a meningioma.

Common questions

What is the link between Depo-Provera and brain tumors?

A 2024 study found that prolonged use of medroxyprogesterone acetate, the active ingredient in Depo-Provera, was associated with a significantly higher risk of intracranial meningioma. The FDA added a meningioma warning to the label in December 2025.

There's a settlement. Can I still file?

The June 2026 settlement in principle covers eligible cases already in the federal MDL and does not resolve every case; state-court options may remain. Whether you can still file depends on your situation, which the attorney review evaluates.

How long did I need to use Depo-Provera?

The scientific link is strongest with prolonged use, generally a year or more. The eligibility check and attorney review sort out whether your history fits.

What kind of brain tumor qualifies?

Meningioma is the core diagnosis. Other brain-tumor diagnoses are reviewed case by case.

I don't have my injection records. Is that a problem?

Usually not disqualifying. Pharmacy and clinic records can often be retrieved, and a sworn declaration about your injection history helps. The intake team assists with records.

Do I need a lawyer first, or do you connect me?

We connect you. The check routes qualified cases to a Depo-Provera-experienced attorney, and you can accept or decline.

What does this cost me?

Nothing. We get paid by the law firms or affiliate fees from the court-appointed administrator. You pay zero up front and zero out of any payout you receive.

Will lawyers spam-call me?

Only if you check the consent box. We give you the choice. If you do not consent, your claim is captured and we route it to the administrator directly without sharing your phone number.

Can I file directly without you?

Yes, always. If we route your claim to a law firm, you can choose to file directly with the same firm or pick a different one. We exist because most people throw the notice letter away. We make it not happen.

Is claimscout a law firm?

No. We are not a law firm and do not provide legal advice. We are a platform that captures your claim, qualifies it, and routes it to the court-appointed administrator or a law firm of your choice.

See if you qualify for a Depo-Provera claim →