{"data":{"matter":{"matter_id":"mat_ead13a2aadc579","slug":"tepezza-hearing-loss","name":"Tepezza Hearing Loss","category":"mass_tort","subcategory":"pharma","status":"litigated","score":0.6,"score_30d":0.5296,"velocity":-0.2314,"headline":"Tepezza hearing loss - MDL alleges the thyroid-eye-disease drug causes permanent hearing damage","summary":"Tepezza (teprotumumab), a Horizon Therapeutics infusion drug for thyroid eye disease, is alleged to cause permanent hearing loss and tinnitus that the label failed to adequately warn about. The federal cases are consolidated in an MDL in the Northern District of Illinois. Eligibility centers on having been treated with Tepezza infusions and later developing hearing loss or tinnitus.","eligibility_hint":"Were treated with Tepezza infusions and developed hearing loss or tinnitus","payout":{"band":"mass_tort","low_cents":5000000,"high_cents":100000000,"low_usd":50000,"high_usd":1000000},"keywords":{"products":["tepezza","teprotumumab","thyroid eye disease","hearing loss","tinnitus"],"brands":["horizon therapeutics","amgen"]},"links":{"primary":"https://www.ilnd.uscourts.gov/","self":"https://getclaimscout.com/api/v1/matters/tepezza-hearing-loss","html":"https://getclaimscout.com/matters/tepezza-hearing-loss","lp":null},"lifecycle":{"first_seen_iso":"2026-07-07T10:06:26Z","last_signal_iso":"2026-08-15T06:41:19Z","mdl_filed_iso":null,"settlement_announced_iso":null,"claims_open_iso":null,"claims_close_iso":null,"narrative_generated_iso":"2026-07-07T10:06:26Z"},"attached_cases_count":0,"embedding_model":null,"embedding_version":1,"schema_version":1},"attached_cases":[],"recent_signals":[{"signal_id":"sig_7299495e9e678b","matter_id":"mat_ead13a2aadc579","source":"courtlistener_search","source_id":"cl-search:73295952","kind":"court_filing","title":"CL filing: In Re Instructure Data Breach Litigation","summary":"Federal filing in utd, docket 2:26-cv-00374, dated 2026-05-05.","url":"https://www.courtlistener.com/recap/?q=combat arms earplugs","score":0.75,"decayed_score":null,"keywords":{"brands":[],"products":[]},"provenance":{"feed":"courtlistener_v4_search","court":"utd","docket_no":"2:26-cv-00374","date_filed":"2026-05-05","source_url":"https://www.courtlistener.com/recap/?q=tepezza","retrieved_at":"2026-09-01T11:20:58Z","search_query":"tepezza"},"resolved_by":"search_context","resolution_confidence":0.3,"first_seen_iso":"2026-08-15T06:41:19Z","last_seen_iso":"2026-09-01T11:20:58Z","schema_version":1},{"signal_id":"sig_0b116c7fba5470","matter_id":"mat_ead13a2aadc579","source":"fda_faers","source_id":"faers:26934447","kind":"adverse_event_report","title":"FAERS: tepezza - Exophthalmos, Muscle spasms, Autophony, Lacrimation increased, Ocular hyperaemia","summary":"FDA Adverse Event Report ID 26934447. Reactions: Exophthalmos, Muscle spasms, Autophony, Lacrimation increased, Ocular hyperaemia. Outcome flagged as: death / life-threatening / hospitalization / disabling.","url":"https://open.fda.gov/data/faers/?search=safetyreportid:26934447","score":0.85,"decayed_score":null,"keywords":{"brands":["horizon therapeutics","amgen"],"products":["tepezza","teprotumumab","thyroid eye disease","hearing loss","tinnitus"]},"provenance":{"feed":"fda_openfda_faers","outcome":"death / life-threatening / hospitalization / disabling","reactions":["Exophthalmos","Muscle spasms","Autophony","Lacrimation increased","Ocular hyperaemia","Ageusia","Eye irritation"],"drug_query":"tepezza","source_url":"https://open.fda.gov/data/faers/?search=safetyreportid:26934447","receivedate":"20260629","retrieved_at":"2026-09-01T11:12:09Z","safetyreportid":"26934447"},"resolved_by":"search_context","resolution_confidence":0.3,"first_seen_iso":"2026-08-04T08:37:25Z","last_seen_iso":"2026-09-01T11:12:09Z","schema_version":1},{"signal_id":"sig_0d01941778e9a6","matter_id":"mat_ead13a2aadc579","source":"fda_faers","source_id":"faers:26938370","kind":"adverse_event_report","title":"FAERS: tepezza - Hypoacusis, Nonspecific reaction","summary":"FDA Adverse Event Report ID 26938370. Reactions: Hypoacusis, Nonspecific reaction. Outcome flagged as: death / life-threatening / hospitalization / disabling.","url":"https://open.fda.gov/data/faers/?search=safetyreportid:26938370","score":0.85,"decayed_score":null,"keywords":{"brands":["horizon therapeutics","amgen"],"products":["tepezza","teprotumumab","thyroid eye disease","hearing loss","tinnitus"]},"provenance":{"feed":"fda_openfda_faers","outcome":"death / life-threatening / hospitalization / disabling","reactions":["Hypoacusis","Nonspecific reaction"],"drug_query":"tepezza","source_url":"https://open.fda.gov/data/faers/?search=safetyreportid:26938370","receivedate":"20260629","retrieved_at":"2026-09-01T11:12:09Z","safetyreportid":"26938370"},"resolved_by":"search_context","resolution_confidence":0.3,"first_seen_iso":"2026-08-04T08:37:25Z","last_seen_iso":"2026-09-01T11:12:09Z","schema_version":1},{"signal_id":"sig_8d4cf9ddcc7a76","matter_id":"mat_ead13a2aadc579","source":"fda_faers","source_id":"faers:26939310","kind":"adverse_event_report","title":"FAERS: tepezza - Toxic goitre","summary":"FDA Adverse Event Report ID 26939310. Reactions: Toxic goitre. Outcome flagged as: death / life-threatening / hospitalization / disabling.","url":"https://open.fda.gov/data/faers/?search=safetyreportid:26939310","score":0.85,"decayed_score":null,"keywords":{"brands":["horizon therapeutics","amgen"],"products":["tepezza","teprotumumab","thyroid eye disease","hearing loss","tinnitus"]},"provenance":{"feed":"fda_openfda_faers","outcome":"death / life-threatening / hospitalization / disabling","reactions":["Toxic goitre"],"drug_query":"tepezza","source_url":"https://open.fda.gov/data/faers/?search=safetyreportid:26939310","receivedate":"20260629","retrieved_at":"2026-09-01T11:12:09Z","safetyreportid":"26939310"},"resolved_by":"search_context","resolution_confidence":0.3,"first_seen_iso":"2026-08-04T08:37:25Z","last_seen_iso":"2026-09-01T11:12:09Z","schema_version":1},{"signal_id":"sig_4125ad875d936b","matter_id":"mat_ead13a2aadc579","source":"fda_faers","source_id":"faers:26942400","kind":"adverse_event_report","title":"FAERS: tepezza - Toxic goitre, Depression, Anxiety, Retinal disorder, Thyroxine free decreased","summary":"FDA Adverse Event Report ID 26942400. Reactions: Toxic goitre, Depression, Anxiety, Retinal disorder, Thyroxine free decreased. Outcome flagged as: death / life-threatening / hospitalization / disabling.","url":"https://open.fda.gov/data/faers/?search=safetyreportid:26942400","score":0.85,"decayed_score":null,"keywords":{"brands":["horizon therapeutics","amgen"],"products":["tepezza","teprotumumab","thyroid eye disease","hearing loss","tinnitus"]},"provenance":{"feed":"fda_openfda_faers","outcome":"death / life-threatening / hospitalization / disabling","reactions":["Toxic goitre","Depression","Anxiety","Retinal disorder","Thyroxine free decreased","Tri-iodothyronine free decreased","Blood thyroid stimulating hormone increased","Abdominal pain","Bone pain","Diarrhoea","Eye swelling","Alopecia","Headache","Lethargy","Muscle spasms","Nausea"],"drug_query":"tepezza","source_url":"https://open.fda.gov/data/faers/?search=safetyreportid:26942400","receivedate":"20260630","retrieved_at":"2026-09-01T11:12:09Z","safetyreportid":"26942400"},"resolved_by":"search_context","resolution_confidence":0.3,"first_seen_iso":"2026-08-04T08:37:25Z","last_seen_iso":"2026-09-01T11:12:09Z","schema_version":1},{"signal_id":"sig_97ede8d3b53f9c","matter_id":"mat_ead13a2aadc579","source":"fda_faers","source_id":"faers:26935923","kind":"adverse_event_report","title":"FAERS: tepezza - Exophthalmos, Diplopia, Thyroid disorder","summary":"FDA Adverse Event Report ID 26935923. Reactions: Exophthalmos, Diplopia, Thyroid disorder. Outcome flagged as: death / life-threatening / hospitalization / disabling.","url":"https://open.fda.gov/data/faers/?search=safetyreportid:26935923","score":0.85,"decayed_score":null,"keywords":{"brands":["horizon therapeutics","amgen"],"products":["tepezza","teprotumumab","thyroid eye disease","hearing loss","tinnitus"]},"provenance":{"feed":"fda_openfda_faers","outcome":"death / life-threatening / hospitalization / disabling","reactions":["Exophthalmos","Diplopia","Thyroid disorder"],"drug_query":"tepezza","source_url":"https://open.fda.gov/data/faers/?search=safetyreportid:26935923","receivedate":"20260629","retrieved_at":"2026-09-01T11:12:09Z","safetyreportid":"26935923"},"resolved_by":"search_context","resolution_confidence":0.3,"first_seen_iso":"2026-08-04T08:37:25Z","last_seen_iso":"2026-09-01T11:12:09Z","schema_version":1},{"signal_id":"sig_6659524aa41320","matter_id":"mat_ead13a2aadc579","source":"fda_faers","source_id":"faers:26941253","kind":"adverse_event_report","title":"FAERS: tepezza - Retinal detachment, Fatigue, Off label use, Decreased appetite, Taste disorder","summary":"FDA Adverse Event Report ID 26941253. Reactions: Retinal detachment, Fatigue, Off label use, Decreased appetite, Taste disorder. Outcome flagged as: death / life-threatening / hospitalization / disabling.","url":"https://open.fda.gov/data/faers/?search=safetyreportid:26941253","score":0.85,"decayed_score":null,"keywords":{"brands":["horizon therapeutics","amgen"],"products":["tepezza","teprotumumab","thyroid eye disease","hearing loss","tinnitus"]},"provenance":{"feed":"fda_openfda_faers","outcome":"death / life-threatening / hospitalization / disabling","reactions":["Retinal detachment","Fatigue","Off label use","Decreased appetite","Taste disorder","Alopecia","Eye swelling","Diplopia","Visual impairment","Lacrimation increased","Unevaluable event"],"drug_query":"tepezza","source_url":"https://open.fda.gov/data/faers/?search=safetyreportid:26941253","receivedate":"20260630","retrieved_at":"2026-09-01T11:12:09Z","safetyreportid":"26941253"},"resolved_by":"search_context","resolution_confidence":0.3,"first_seen_iso":"2026-08-04T08:37:25Z","last_seen_iso":"2026-09-01T11:12:09Z","schema_version":1},{"signal_id":"sig_8628bdd327fe87","matter_id":"mat_ead13a2aadc579","source":"fda_faers","source_id":"faers:26938427","kind":"adverse_event_report","title":"FAERS: tepezza - Muscle spasms, Dry skin, Tinnitus, Tinnitus","summary":"FDA Adverse Event Report ID 26938427. Reactions: Muscle spasms, Dry skin, Tinnitus, Tinnitus. Outcome flagged as: death / life-threatening / hospitalization / disabling.","url":"https://open.fda.gov/data/faers/?search=safetyreportid:26938427","score":0.85,"decayed_score":null,"keywords":{"brands":["horizon therapeutics","amgen"],"products":["tepezza","teprotumumab","thyroid eye disease","hearing loss","tinnitus"]},"provenance":{"feed":"fda_openfda_faers","outcome":"death / life-threatening / hospitalization / disabling","reactions":["Muscle spasms","Dry skin","Tinnitus","Tinnitus"],"drug_query":"tepezza","source_url":"https://open.fda.gov/data/faers/?search=safetyreportid:26938427","receivedate":"20260629","retrieved_at":"2026-09-01T11:12:09Z","safetyreportid":"26938427"},"resolved_by":"search_context","resolution_confidence":0.3,"first_seen_iso":"2026-08-04T08:37:25Z","last_seen_iso":"2026-09-01T11:12:09Z","schema_version":1},{"signal_id":"sig_7fbce6fafa2f57","matter_id":"mat_ead13a2aadc579","source":"fda_faers","source_id":"faers:26947111","kind":"adverse_event_report","title":"FAERS: tepezza - Breast cancer","summary":"FDA Adverse Event Report ID 26947111. Reactions: Breast cancer. Outcome flagged as: death / life-threatening / hospitalization / disabling.","url":"https://open.fda.gov/data/faers/?search=safetyreportid:26947111","score":0.85,"decayed_score":null,"keywords":{"brands":["horizon therapeutics","amgen"],"products":["tepezza","teprotumumab","thyroid eye disease","hearing loss","tinnitus"]},"provenance":{"feed":"fda_openfda_faers","outcome":"death / life-threatening / hospitalization / disabling","reactions":["Breast cancer"],"drug_query":"tepezza","source_url":"https://open.fda.gov/data/faers/?search=safetyreportid:26947111","receivedate":"20260630","retrieved_at":"2026-09-01T11:12:09Z","safetyreportid":"26947111"},"resolved_by":"search_context","resolution_confidence":0.3,"first_seen_iso":"2026-08-04T08:37:25Z","last_seen_iso":"2026-09-01T11:12:09Z","schema_version":1},{"signal_id":"sig_2b37f0b162ce82","matter_id":"mat_ead13a2aadc579","source":"google_news","source_id":"gnews:CBMihwFBVV95cUxOOGhIZ3BSQ25BLWJyUmxJZzJRYjZ4ZDk1ell0WTY1S05wdzVOb29zRmlEclZNR0poMFpBdWptN1pmemJKNU5rTVFpMkZnenlTLUtYS0lzZkJxUEVibzlMc2w5WmpGNDF0b0ZrdnlrdEhtckxDZW82Vm5PY1oyN19yZXZ0S25UM0E","kind":"news_article","title":"Eye Disease Medication Tepezza Linked to Hearing Loss | Console and Associates, P.C. - JD Supra","summary":"Eye Disease Medication Tepezza Linked to Hearing Loss | Console and Associates, P.C.    JD Supra","url":"https://news.google.com/rss/articles/CBMihwFBVV95cUxOOGhIZ3BSQ25BLWJyUmxJZzJRYjZ4ZDk1ell0WTY1S05wdzVOb29zRmlEclZNR0poMFpBdWptN1pmemJKNU5rTVFpMkZnenlTLUtYS0lzZkJxUEVibzlMc2w5WmpGNDF0b0ZrdnlrdEhtckxDZW82Vm5PY1oyN19yZXZ0S25UM0E?oc=5","score":0.55,"decayed_score":null,"keywords":{"brands":["horizon therapeutics","amgen"],"products":["tepezza","teprotumumab","thyroid eye disease","hearing loss","tinnitus"]},"provenance":{"feed":"google_news_rss","published":"Tue, 20 Dec 2022 08:00:00 GMT","source_url":"https://news.google.com/rss/articles/CBMihwFBVV95cUxOOGhIZ3BSQ25BLWJyUmxJZzJRYjZ4ZDk1ell0WTY1S05wdzVOb29zRmlEclZNR0poMFpBdWptN1pmemJKNU5rTVFpMkZnenlTLUtYS0lzZkJxUEVibzlMc2w5WmpGNDF0b0ZrdnlrdEhtckxDZW82Vm5PY1oyN19yZXZ0S25UM0E?oc=5","retrieved_at":"2026-08-25T06:43:52Z","search_query":"\"tepezza\" (lawsuit OR settlement OR recall OR \"class action\")"},"resolved_by":"auto","resolution_confidence":0.49375,"first_seen_iso":"2026-08-04T08:35:37Z","last_seen_iso":"2026-08-25T06:43:52Z","schema_version":1},{"signal_id":"sig_d0b92b927f9125","matter_id":"mat_ead13a2aadc579","source":"google_news","source_id":"gnews:CBMihwFBVV95cUxOeDBuYUE4eTVCSzBhOHBxQy1SR3pLX25najBJSUJMbkZoNUNkMmp4eTd5S3FPcHhlc2NSZVZIQ0J5TW1oWFZsZ19aNVktUUhkRFg4R1BwRGxFSzk3bkUyTHBLRlVsWk9CZmtIcUNGYk9vRjNBcThVT3NUNi1JRTRLSmxuUUlob2M","kind":"news_article","title":"Horizon Therapeutics Faces Tepezza Lawsuits for Hearing Loss, Tinnitus - Drugwatch.com","summary":"Horizon Therapeutics Faces Tepezza Lawsuits for Hearing Loss, Tinnitus    Drugwatch.com","url":"https://news.google.com/rss/articles/CBMihwFBVV95cUxOeDBuYUE4eTVCSzBhOHBxQy1SR3pLX25najBJSUJMbkZoNUNkMmp4eTd5S3FPcHhlc2NSZVZIQ0J5TW1oWFZsZ19aNVktUUhkRFg4R1BwRGxFSzk3bkUyTHBLRlVsWk9CZmtIcUNGYk9vRjNBcThVT3NUNi1JRTRLSmxuUUlob2M?oc=5","score":0.55,"decayed_score":null,"keywords":{"brands":["horizon therapeutics","amgen"],"products":["tepezza","teprotumumab","thyroid eye disease","hearing loss","tinnitus"]},"provenance":{"feed":"google_news_rss","published":"Mon, 14 Nov 2022 08:00:00 GMT","source_url":"https://news.google.com/rss/articles/CBMihwFBVV95cUxOeDBuYUE4eTVCSzBhOHBxQy1SR3pLX25najBJSUJMbkZoNUNkMmp4eTd5S3FPcHhlc2NSZVZIQ0J5TW1oWFZsZ19aNVktUUhkRFg4R1BwRGxFSzk3bkUyTHBLRlVsWk9CZmtIcUNGYk9vRjNBcThVT3NUNi1JRTRLSmxuUUlob2M?oc=5","retrieved_at":"2026-09-01T11:10:23Z","search_query":"\"tepezza\" (lawsuit OR settlement OR recall OR \"class action\")"},"resolved_by":"auto","resolution_confidence":0.625,"first_seen_iso":"2026-07-16T08:12:19Z","last_seen_iso":"2026-09-01T11:10:23Z","schema_version":1},{"signal_id":"sig_30bb11cb1f7a68","matter_id":"mat_ead13a2aadc579","source":"google_news","source_id":"gnews:CBMilAFBVV95cUxNNVdVZHVRank0WlhoNENfa2lyR2VMekZ4bUtVY2F5LUJVUlp2b2RfeGR0elBvRG9qamRkLVQ3TXBKT0IwQTdLZWladnBHekdEWmt2UDc2WThqV1poOG1HOGt4TGdKeGllTVdkQmxRSm9UREN5UnRlQ3docDZQX1ZzcVBoTktlUlNUNnlCcXNsbUJCLXc5","kind":"news_article","title":"FDA adds new warning to Tepezza label - 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Express Scripts, Inc.","summary":"Federal filing in ilnd, docket 1:26-cv-01718, dated 2026-02-17.","url":"https://www.courtlistener.com/recap/?q=tepezza","score":0.75,"decayed_score":null,"keywords":{"brands":[],"products":[]},"provenance":{"feed":"courtlistener_v4_search","court":"ilnd","docket_no":"1:26-cv-01718","date_filed":"2026-02-17","source_url":"https://www.courtlistener.com/recap/?q=tepezza","retrieved_at":"2026-09-01T11:20:58Z","search_query":"tepezza"},"resolved_by":"search_context","resolution_confidence":0.3,"first_seen_iso":"2026-07-08T08:36:57Z","last_seen_iso":"2026-09-01T11:20:58Z","schema_version":1},{"signal_id":"sig_fc4535d0494064","matter_id":"mat_ead13a2aadc579","source":"courtlistener_search","source_id":"cl-search:72153472","kind":"court_filing","title":"CL filing: Sagebrush Health Services v. Amgen Inc.","summary":"Federal filing in cacd, docket 2:26-cv-00466, dated 2026-01-16.","url":"https://www.courtlistener.com/recap/?q=tepezza","score":0.75,"decayed_score":null,"keywords":{"brands":[],"products":[]},"provenance":{"feed":"courtlistener_v4_search","court":"cacd","docket_no":"2:26-cv-00466","date_filed":"2026-01-16","source_url":"https://www.courtlistener.com/recap/?q=tepezza","retrieved_at":"2026-09-01T11:20:58Z","search_query":"tepezza"},"resolved_by":"search_context","resolution_confidence":0.3,"first_seen_iso":"2026-07-08T08:36:57Z","last_seen_iso":"2026-09-01T11:20:58Z","schema_version":1},{"signal_id":"sig_f03e0786b0562b","matter_id":"mat_ead13a2aadc579","source":"courtlistener_search","source_id":"cl-search:72533633","kind":"court_filing","title":"CL filing: IN RE: Nitrogen, Phosphorus, and Potassium (NPK) Fertilizer Antitrust Litigation","summary":"Federal filing in jpml, docket MDL No. 3187, dated 2026-03-19.","url":"https://www.courtlistener.com/recap/?q=tepezza","score":0.75,"decayed_score":null,"keywords":{"brands":[],"products":[]},"provenance":{"feed":"courtlistener_v4_search","court":"jpml","docket_no":"MDL No. 3187","date_filed":"2026-03-19","source_url":"https://www.courtlistener.com/recap/?q=tepezza","retrieved_at":"2026-09-01T11:20:58Z","search_query":"tepezza"},"resolved_by":"search_context","resolution_confidence":0.3,"first_seen_iso":"2026-07-08T08:36:57Z","last_seen_iso":"2026-09-01T11:20:58Z","schema_version":1},{"signal_id":"sig_f973cd61c98776","matter_id":"mat_ead13a2aadc579","source":"fda_faers","source_id":"faers:26549084","kind":"adverse_event_report","title":"FAERS: tepezza - Thyrotoxic crisis","summary":"FDA Adverse Event Report ID 26549084. 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